Ester-c is a breakthrough patented vitamin c formula supported with naturally occurring metabolites. Metabolites help enhance the retention of vitamin c by your white blood cells, an important part of your immune system. Unique, chemical-free manufacturing process neutralizes ph, making it non-acidic and gentle on the stomach. In a daily 1,000 mg dose, ester-c delivers 24-hour immune support, so once a day is all you need. Each 2 vegetarian tablets contain 1,000 mg vitamin c (as ester-c calcium ascorbate) and 110 mg calcium (as ester-c calcium ascorbate). Take 2 tablets once daily, preferably with a meal.