No refrigeration needed! 5 billion live cultures designed to survive stomach acids. Features true delivery technology that ensures active cultures survive stomach acids, arrive in the intestines and thrive to provide exceptional support. The proprietary blend of lactobacillus Plantarum lp-115, Bifidobacterium lactis bl-04, b. Longum bb536, and l. Acidophilus nfcm helps balance intestinal microflora for digestive system health and boosting of natural body defenses. A healthy digestive system supports a favorable environment for the absorption of nutrients and helps to support a healthy immune system. Supports digestive function and helps cleanse the intestinal tract. Take 1 soft gel daily with or without food.